LOSS OF P19(ARF) FACILITATES THE ANGIOGENIC SWITCH AND TUMOR INITIATION IN A MULTI-STAGE CANCER MODEL VIA P53-DEPENDENT AND INDEPENDENT MECHANISMS.

Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms.

The Arf tumor suppressor acts as a sensor of oncogenic signals, countering aberrant proliferation in large part via activation of the p53 transcriptional program, though a number of p53-independent functions jazz hands bold loropetalum have been described.Mounting evidence suggests that, in addition to promoting tumorigenesis via disruptions in the

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Lithospheric electrical structure across the Bangong-Nujiang Suture in northern tibet revealed by magnetotelluric

Competing hypotheses have been proposed to explain the subduction polarity of the Bangong-Nujiang Tethyan Ocean and the formation of the high-conductivity anomaly beneath the Qiangtang terrane.However, the lithospheric architecture of the northern Tibetan Plateau is still poorly understood due to inhospitable environments and topography.Therefore,

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Research on Tropical Medicine and Germ Theory in Colonial Hong Kong: Focusing on Malaria and Plague Prevention

At the end of the nineteenth century, Hong Kong was in the insulated debakey midst of a malaria and plague epidemic which caused a fierce dispute within the medical community over disease theories and quarantine practices.However, the Hong Kong colonial authorities and medical community did not immediately accept the theory of etiology based on ger

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Law Enforcement for Culinary Business Actors for Violations in Obligations in Implementing Education and Protocol of Covid-19 Prevention in Jakarta

The Special Capital Region of Jakarta (Indonesian: Daerah Khusus Ibukota/DKI Jakarta) has various regulations in enforcing the health protocol law, imposing sanctions on culinary business actors for various violations committed, in terms of not carrying out educational obligations and Covid.-19 prevention protocols.The problems in this research are

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